Endocrine Abstracts

Introduction: Retrospective study of patients undergoing thyroid surgery at the Hospital Virgen de la Luz, Cuenca (Spain) during the years 2010–2013.Material and methods: We evaluated data of 92 patients basically with nodular thyroid disease, who were studied and treated in our hospital.Results: Our series is made up of 92 patients (25% men and 75% women) with an average age of 52 years. The most common form of presentation (...

Introduction, material and methods: Papillary thyroid cancer is well known to be a tumour with a good prognosis; in spite of that, it usually presents many recurrences that increases its morbidity. Follicular thyroid cancer is less frequent but has a higher rate of hematogenous dissemination and higher mortality than papillary thyroid cancer. We have collected the data of our patients with differentiated thyroid cancer during the period from 2000 to 2015. In this study, we hav...

Background: Pancreatic Cancer (PC) is uncommon; however, it is one of the most deadly cancer types of all. New-onset diabetes (NOD) is associated with a higher risk of pancreatic cancer than general population, particularly if late-onset. An association between new-onset diabetes and increased mortality in patients with pancreatic cancer has been suggested but clinical relevant differences between those individuals with new-onset diabetes and those without are not well establi...

Introduction, material and methods: The BRAF isoform of RAF has been implicated in the pathogenesis of papillary thyroid cancer, but not of benign or follicular neoplasms. Also, BRAF mutations may confer a worse clinical prognosis than for papillary thyroid cancer without the BRAF mutation. Recurrence occurs more frequently when BRAF mutations are present. In addition, BRAF mutations are associated with extrathyroidal invasion, lymph node me...

Background: Acid-labile subunit (ALS) deficiency inhibits ternary complex formation leading to primary IGF1 deficiency and short stature. Potential metabolic consequences such as diabetes and low bone mass are not well studied.Objective: This study measured insulin sensitivity, lipid profile, bone density and structure in members of 4 affected families and explore possible gene-dose effects.Methods: Four patients (7–21 years) ...

Introduction: Endonasal endoscopic transsphenoidal surgery (EETS) for a sellar or suprasellar mass poses potential complications, including transient or permanent hypopituitarism. Adrenocortical insufficiency is especially worrisome given its potentially life-threatening course, if untreated. Usual clinical practice includes administration of perioperative “stress doses” of steroids followed by long term steroid replacement until the hypothalamic-pituitary-adrenal ax...

Introduction: Bariatric surgery is currently considered the most effective treatment for morbid obesity. Laparoscopic gastric bypass (LGB) and laparoscopic sleeve gastrectomy (LSG) are the most widely used bariatric procedures today.Objectives: In this study we compared LGB and LSG in order to establish whether there is any superiority of one or the other in effectiveness and complications.Methods: We included all the patients who ...

Introduction: Bariatric surgery is currently considered the most effective treatment for morbid obesity, although rates of weight loss and comorbidities resolution differ among bariatric techniques and depending on preoperative factors.Objectives: In this study we analyse possible factors that influence the outcome of bariatric surgery (weight loss and improvement in metabolic comorbidities) in order to identify those patients most likely to benefit from...